2005

Kaarina Viljanen:
Protein oxidation and protein-lipid interactions in different food models in the presence of berry phenolics.
University of Helsinki, Faculty of Agriculture and Forestry, Department of Applied Chemistry and Microbiology. Supervisor Prof. Marina Heinonen.

Satu Vuorela:
Analysis, isolation, and bioactivities of rapeseed phenolics.
University of Helsinki, Faculty of Agriculture and Forestry, Department of Applied Chemistry and Microbiology, Food Chemistry. Supervisor Prof. Marina Heinonen.

2004

Mari Charlotte Wik Myhrstad:
Regulation of cellular glutathione synthesis by dietary polyphenols.
Institute for Nutrition Research, Faculty of Medicine, University of Oslo. Supervisor: Prof. Rune Blomhoff.

2003

Arnar Halldorsson:
Lipase Selectivity in Lipid Modification.
Science Institute, University of Iceland, Dunhaga 3, IS-107 Reykjavík, Iceland, Supervisor: Prof. Gudmundur G. Haraldsson.

Harald Carlsen:
Diet and gene regulation: Molecular imaging and gene expression in transgenic reporter mice.
Institute for Nutrition Research, Faculty of Medicine, University of Oslo. Supervisor: Prof. Rune Blomhoff.

Paula Berstad:
Serum non-esterified fatty acid pattern and risk of coronary heart disease
Institute for Nutrition Research, Faculty of Medicine, University of Oslo. Supervisor: Prof. J.I. Pedersen

2002

Isabel Aidos:
Production of high-quality fish oil from herring by-products. 
Food and Bioprocess Engineering Group, Wageningen University, the Netherlands. October 2002.

Thien Ngoc Tran:
Regulation of n-3 and n-6 fatty acid metabolism
Institute of Clinical Biochemistry, National University Hospital, University of Oslo. Supervisor:  Prof. B. O. Christophersen.

Hilde Heimili:
Polyunsaturated fatty acids and induction of cell death in leukemia/lymphoma cell lines
Institute for Nutrition Research, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo. Supervisor: Prof. C. A. Drevon.

Kari Anne Risan Tobin:
LXR - a nuclear receptor involved in fatty acid and cholesterol homeostatic pathways
Institute for Nutrition Research, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo. Supervisor: Prof. H. I. Nebb.

Ingrid Bergliot Helland:
Fatty acids, mothers and children
Institute for Nutrition Research, Dept. of Pediatric Research, Faculty of Medicne, University of Oslo. Supervisors: Prof. C. A. Drevon and O. D. Saugstad.

Karl Johan Tronstad:
Effects of the modified fatty acid, tetradecylthioacetic acid (TTA), on cancer cell proliferation and induction of cell death .
Dept. of Clinical Biochemistry, Haukland Hospital, Faculty of Medicine, University of Bergen. Superviser: Prof. R. K. Berge.

Torun Clausen:
Maternal and placental factors and risk of preeclapsia: A prospective study of dietary, lipid, hormonal and inflammatory factors.
Dept. of Obstetrics and Gynecology, Ulleval and Rikshospitalet University Hospitals, Institute for Nutrition Research, University of Oslo. Supervisor: T. Hendriksen.

2001

Erkkilä, Arja:
Diet, serum lipids and serum lipid related risk factors in patients with coronary heart disease. A cross-sectional study.
Kuopio University Publications D. Medical Sciences 233. 2001. 83 p.  ISBN 951-781-813-0, ISSN 1235-0303.  Abstract.

Raffick Amid Razzakk Bowen:
Dietary Linolenic and Docosahexaenoic Acid Influence the Docosahexaenoic Acid Content of Brain Membrane Lipids and Function in Developing Rats.
Abstract.

David Won Lung Ma:
Identification of the Conjugated Linoleic Acid Isomer Responsible for Inhibiting Essential Fatty Acid Metabolism and Tumor Cell Growth.
Abstract.

Maarit Hallikainen:
Role of plant stanol ester- and sterol ester-enriched margarines in the treatment of hypercholesterolemia.
Department of Clinical Nutrition,University of Kuopio and Kuopio University Hospital.
Supervisors Prof. Matti Uusitupa and Docent Essi Sarkkinen Ph.D.
Kuopio University Publications D. Medical Sciences 251. 2001. 90 p.
ISBN 951-781-851-3, ISSN 1235-0303. Abstract:

2000

Kjetil Retterstøl:
Studies on the metabolism of polyunsaturated fatty acids in liver and testicular cells. Elongation, desaturation and esterification. The regulation of the formation of 22:5(N-6) and 22:6(N-3).
Institute of Clinical Biochemistry, Rikshospitalet, University of Oslo, September 2000.
Dr.Med. thesis based on eight papers. ISBN 82-7633-143.2. Supervised by Bjørn Christophersen. 

Anne Cathrine Staff:
Preeclampsia and uteroplacental tissues: Lipids, oxidative stress, and trophoplast invasion.
Institute for Nutrition Research and Department of Obestrics and Gynecology, Aker Hospital, University of Oslo, June 2000.
Dr.Med. thesis based on five papers. ISBN 82-91061-21-1. Supervised by Tore Henriksen.  

Jowita Sleboda:
Effects of Hypolipemic Drugs on Hepatic Fatty Acid Oxidation.
Institute of Medical Biochemistry, University of Oslo, June 2000. Dr.Philos. thesis based on six papers. ISBN 82-91061-18-1. Supervised by Jon Bremer.

The aim of the thesis was to elucidate the mechanism for the hypolipemic effect of 3-thia fatty acids and other peroxisomal proliferators. Data were collected from experiments with hepatocytes in culture and from feeding experiments. Some of the conclusions were as follows: Mitochondrial b-oxidation is affected profoundly by 3-thia fatty acids and a-methyl-3-thia fatty acids through effects on carnitine palmitoyltransferase (CPT) I, and 3-thia fatty acids up-regulate the mRNA expression of CPT I in cultured hepatocytes. It is possible that 3-thia fatty acids induce CPT I gene expression by activating PPARa.  

Hilde Hermansen Steineger:
Studies on nuclear receptors in lipid metabolism. Regulation of gene expression by fatty acids and hormones.
Institute of Medical Biochemistry, University of Oslo, March 2000.
Dr.Philos. thesis based on five papers. ISBN 82-91061-15-7. Supervised by Øystein Spydevold and Kaare M. Gautvik.

Mechanisms for regulation of expression of PPARalfa, RXRalfa and LXRalfa by fatty acids and hormones are studied in this thesis. The studies were mainly conducted on rat liver cells. Some of the conclusions are, that fatty acids and the synthetic glucocorticoid analogue dexamethasone stimulate gene expression of PPARalfa and RXRalfa, and that PPAR/fatty acid signaling transduction mechanisms play a fundamental role in the metabolic cross talk and the energy homeastasis. The findings of the thesis suggest that the activity of PPARalfa, RXRalfa and LXRalfa are tightly controlled by hormonal signalling pathways and the lipid homeostasis.  

Xuebing Xu:
Production of specific structured lipids by lipase-catalyzed interesterification.
Department of Biotechnology, Technical University of Denmark, March 2000.
ISBN 87-88584-43-7. Supervised by Jens-Adler-Nissen, Carl-Erik Høy and Gunnar Jonsson.

Specific structured lipids are defined as any triacylglycerols containing both long, medium and short chain fatty acids, in which each fatty acid is located spesifically at the sn-1,3 or sn-2 positions of the glycerol backbone. The main theme was focused on the practicality and technological feasibility of large-scale production of high-quality products. The thesis consists of studies on reaction systems and reactors for the synthesis of specific structured lipids.  

Anette Bysted:
Trans fatty acids versus saturated fatty acids in the diet. Relations to the metabolism of polyunsaturated fatty acids and blood lipids.
Department of Biochemistry and Nutrition, Technical University of Denmark, 2000.
Dr.Philos. thesis based on five papers. Supervised by Gunhild Hølmer.

The thesis consists of three parts. In a study on effects of dietary trans fatty acids on the formation of PUFA in rats, it was found out that the conversion of linoleic acid to arachidonic acid was dependent on the amount and origin of dietary trans fatty acids. In two human postprandial studies, effect of intake of different fatty acids on triacyglycerols for chylomicrons and VLDL were investigated. In a study on adipose tissue fatty acid composition in women with and without breast cancer, it was found out that there was no indication of a relation between total trans fatty acids, SFA, MUFA or PUFA in adipose tissue and risk of breast cancer.  

1999

Lars Ellegård:
Dietary effects on cholesterol absorption and excretion. Studies in ileostomy subjects.
Department of Clinical Nutrition, Institute of Internal Medicine, Sahlgrenska University Hospital, Göteborg University. ISBN 91-628-3885-7.  

Stefan Söderberg:
Leptin - a risk marker for cardiovascular disease.
Department of Public Health and Clinical Medicine, Medicine, Umeå University, September 1999. ISBN 91-7191-673-3.  

Nina Skall Nielsen:
Influence of rapeseed oil on human lipoprotein metabolism. Absorption of rapeseed oil and influence on oxidation of lipoproteins.
Department of Biochemistry and Nutrition, Technical University of Denmark.

The effect of rapeseed oil (RO) diet and control fat diets on plasma lipids fatty acid composition and lipoprotein resistance to oxidation were studied in dietary trials. Acute intake of the fats resulted in an increase in plasma TG level and plasma chylomicron and VLDL fatty acid compositions to reflect the compositions of the fats. Longer periods of intervention were required to affect the fatty acid composition of LDL. Three-week intake of RO diet resulted in a decreased propagation rate in LDL oxidation compared to sunflower oil diet, but not in difference compared to olive oil diet. Plasma and lipoprotein levels of g-tocopherol were increased after intake of RO compared with the other fats tested (sunflower, olive and palm oil and butter). The effects on plasma a-tocopherol levels were not as obvious.  

Charlotte Jacobsen:
Oxidation mechanisms in fish oil enriched emulsions.
Department of Seafood Research, Danish Institute for Fisheries Research/BioCentrum-DTU.
Abstract: